Development of live attenuated thermostable lentogenic strain Newcastle disease vaccine (local isolate) – West Bengal University of Animal and Fishery Sciences

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Case Study

Development of live attenuated thermostable lentogenic strain Newcastle disease vaccine (local isolate) for the village chicken

West Bengal University of Animal and Fishery Sciences developed the Newcastle disease vaccine 

Problems:

Problem arises when frequent reports of Newcastle disease outbreaks come throughout the year from all over the country in spite of performing routine vaccination against the disease using live vaccines. Because of this disease, village chicken farmers are disheartened by the loss of a large number of their birds that often occur on an annual basis.

Solutions:

The vaccine has been developed using the locally isolated lentogenic strain of the Newcastle disease virus, the developed thermostable vaccine induces protective immunity in poultry birds in the field and its conditions also.

Outcomes:

Because of this vaccine backyard birds became able to withstand the challenge of infection of velogenic pathotype of NDV (local isolate). And, it does not require strict maintenance of cold chain facilities in the field conditions.

Challenges:

The major challenge was procurement of its Specific Pathogen Free (SPF) eggs.

Innovations:

The live attenuated thermostable lentogenic strain ND vaccine (local isolate) was absolutely safe and produces optimal immune response in backyard birds when administered intranasally in village level. Also, it had the highest performance in comparison to available commercial ND vaccines.

Opportunities:

The vaccine was used in the selected villages in 2 districts of the state of West Bengal and could be widely used all over the country. 

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For more information, please contact:
Dr Chanchal Guha at profcguha@gmail.com

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